Components

Grammar detail: 抜きに, 抜きにして, 抜きで

抜きに, 抜きにして, 抜きで
96 words
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noun or phrase A + 抜きに, 抜きにして, 抜きで + phrase B
are all ways to say
without A, B is ~
This is a common way to say that without A, B is difficult, or cannot proceed etc. For example:
かのじょ
彼女
しあい
試合
けっしょうせん
決勝戦
まさ
てる
とは
おも
えない

I don't think we have a chance of winning the key match without her.
せじ
世辞
ジョンさん
にほんご
日本語
ネイティブ
すごい
In all seriousness, John's Japanese is native level.
It is sometimes used as a way to say 'regardless of A, B went ahead'. For example:
かれ
その
こじいん
孤児院
けんちく
建築
そんとくかんじょう
損得勘定
けた

He built an orphanage regardless of any business merit.
The difference between にして and で is one of intent. で implies that the situation is that A is not present. にして implies that the speaker is actively excluding A. For example:
この
けいかく
計画
かれ
では
すす
められない

This plan cannot proceed without him.
この
けいかく
計画
かれ
きにして
すす
められない

If we exclude him, this plan cannot proceed.
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Kanji used in this grammar

バツ   ぬ to extract, pull out   ぬける to come / fall out; be omitted   ぬかす to omit   ぬかる to make a blunder   
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ヒ   かれ he   
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ジョ   ニョ   ニョウ   woman; female   おんな woman   め woman   
シ   ため to test   こころみる to attempt   
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ゴウ   ガッ   カッ   あ to fit, come together   あわす to match   あわせる to unite, join   
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ケツ   きめる to decide   きまる to be decided   
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ショウ   か to win   まさ to be better than   
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セン   いくさ battle, war   たたか to do battle   
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シ   おも to think   
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セ   セイ   よ the world   
ジ   やめる quit   
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ニチ   ジツ   sun; day   ひ    -か    
ホン   book   もと origin   
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ゴ   かた to talk, relate   かたらう to talk together, chat   
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ヘイ   lined up   なら to be lined up, to queue   ならべる to line up   な ordinary; the level of   ならびに as well as   
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コ    alone   
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ジ   ニ    newborn babe   
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イン    institution   
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ケン   コン   た to be built   たてる to build   
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チク   きず to construct, to make   
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ソン   そこなう    そこねる to injure, to harm   
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トク    profit   え    う to acquire   
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カン    intuition   
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テイ   ジョウ   determined   さだ decidedly, truly   さだめる to decide, determine   さだまる to be determined   
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イン   ひ to pull   ひける to be over   
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ジュ   うける to receive, to accept   うかる to pass (an exam)    
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ケイ   はからう to arrange   はか to measure, compute   
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ガ   カク   draw
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シン   すす to advance   すすめる to promote, push   
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