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Grammar detail: 抜きに, 抜きにして, 抜きで

抜きに, 抜きにして, 抜きで
96 words
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noun or phrase A + 抜きに, 抜きにして, 抜きで + phrase B
are all ways to say
without A, B is ~
This is a common way to say that without A, B is difficult, or cannot proceed etc. For example:
かのじょ
彼女
ぬ
抜
き
で、
しあい
試合
の
けっしょうせん
決勝戦
に
まさ
勝
てる
とは
おも
思
えない
。
I don't think we have a chance of winning the key match without her.
お
せじ
世辞
ぬ
抜
き
で、ジョンさんの
にほんご
日本語
はネイティブ
な
並
み
にすごいよ。
In all seriousness, John's Japanese is native level.
It is sometimes used as a way to say 'regardless of A, B went ahead'. For example:
かれ
彼
はその
こじいん
孤児院
の
けんちく
建築
を
そんとくかんじょう
損得勘定
ぬ
抜
き
に
ひ
引
き
う
受
けた
。
He built an orphanage regardless of any business merit.
The difference between にして and で is one of intent. で implies that the situation is that A is not present. にして implies that the speaker is actively excluding A. For example:
この
けいかく
計画
は
かれ
彼
を
ぬ
抜
き
では、
すす
進
められない
。
This plan cannot proceed without him.
この
けいかく
計画
は
かれ
彼
を
ぬ
抜
きにして
は、
すす
進
められない
。
If we exclude him, this plan cannot proceed.
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Kanji used in this grammar

抜
バツ   ぬく to extract, pull out   ぬける to come / fall out; be omitted   ぬかす to omit   ぬかる to make a blunder   
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彼
ヒ   かれ he   
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女
ジョ   ニョ   ニョウ   woman; female   おんな woman   め woman   
試
シ   ためす to test   こころみる to attempt   
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合
ゴウ   ガッ   カッ   あう to fit, come together   あわす to match   あわせる to unite, join   
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決
ケツ   きめる to decide   きまる to be decided   
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勝
ショウ   かつ to win   まさる to be better than   
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戦
セン   いくさ battle, war   たたかう to do battle   
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思
シ   おもう to think   
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世
セ   セイ   よ the world   
辞
ジ   やめる quit   
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日
ニチ   ジツ   sun; day   ひ    -か    
本
ホン   book   もと origin   
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語
ゴ   かたる to talk, relate   かたらう to talk together, chat   
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並
ヘイ   lined up   ならぶ to be lined up, to queue   ならべる to line up   なみ ordinary; the level of   ならびに as well as   
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孤
コ    alone   
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児
ジ   ニ    newborn babe   
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院
イン    institution   
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建
ケン   コン   たつ to be built   たてる to build   
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築
チク   きずく to construct, to make   
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損
ソン   そこなう    そこねる to injure, to harm   
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得
トク    profit   える    うる to acquire   
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勘
カン    intuition   
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定
テイ   ジョウ   determined   さだか decidedly, truly   さだめる to decide, determine   さだまる to be determined   
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引
イン   ひく to pull   ひける to be over   
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受
ジュ   うける to receive, to accept   うかる to pass (an exam)    
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計
ケイ   はからう to arrange   はかる to measure, compute   
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画
ガ   カク   draw
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進
シン   すすむ to advance   すすめる to promote, push   
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